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Nov 10

Top 10 Largest Global Merger & Acquisition Deals – October 2025

  • November 10, 2025
  • Merger & Acquisition ( M&A)

October noticed a surge in mergers and acquisitions, with companies across finance, biotech, AI infrastructure, and energy aggressively expanding through strategic billion-dollar deals.  

Below, we highlight the top 10 largest M&A deals announced in the month, based on Intellizence Mergers & Acquisitions Dataset.   

American Water and Essential Utilities to Merge as a Leading Regulated U.S. Water and Wastewater Utility

Transaction Value: $63 billion

Industry: Energy

The two U.S. water and wastewater giants, American Water and Essential Utilities, are to merge to form a leading regulated U.S. Water and Wastewater Utility, creating a $63 billion regulated utility leader. The transaction strengthens scale, operational efficiency, and the capacity for long-term infrastructure investment. The combined entity aims to modernize aging systems and expand essential utility services across multiple states.

Global Infrastructure Partners (GIP) Acquires Aligned Data Centers for $40 Billion.

Transaction Value: $40 billion

Industry:  Technology

GIP is acquiring Aligned Data Centers in a landmark $40 billion AI-infrastructure bet. The deal accelerates GIP’s presence in hyperscale data center expansion driven by AI compute demand.

Aligned will gain capital and global reach to accelerate new builds across North America and beyond.

Blackstone Acquires Hologic 

Transaction Value: $18.3 billion

Industry: Biotechnology

Blackstone is buying women’s health diagnostics leader Hologic for $18.3 billion. The acquisition gives Blackstone access to high-margin diagnostics and medical devices with strong global demand. Hologic gains greater investment capacity to expand R&D and global commercialization. 

Novartis Acquires Avidity Biosciences

Transaction Value: $12 billion

Industry: Pharmaceuticals

Novartis is acquiring Avidity to strengthen its RNA therapeutics portfolio.

The $12B deal accelerates Novartis’ expansion into precision genetic medicines.

Avidity gains resources to advance its pipeline and scale clinical programs rapidly.

Fifth Third Bank to Acquire Comerica Bank for $10.9 Billion

Transaction Value: $10.9 Billion

Industry: Banking

Fifth Third is acquiring regional rival Comerica in a $10.9 billion transaction. The merger expands Fifth Third’s footprint across key U.S. commercial banking markets. The combined bank expects cost synergies, a stronger deposit franchise, and enhanced digital offerings.

Berkshire Hathaway Acquires Occidental Petroleum’s OxyChem Unit

Transaction Value: $9.7 Billion

Industry: Telecommunication

Berkshire Hathaway is purchasing OxyChem, the chemical manufacturing unit of Occidental Petroleum. The $9.7 billion acquisition expands Berkshire’s industrial and chemicals portfolio.

OxyChem gains long-term stability under Berkshire’s operating model.

Thermo Fisher Scientific Acquires Clario Holdings

Transaction Value: $8.9 Billion

Industry: Biotechnology

Thermo Fisher is acquiring clinical research technology provider Clario for $8.9B.

The deal expands Thermo Fisher’s digital clinical trial and patient data capabilities.

Clario gains scale and integration into Thermo Fisher’s global scientific ecosystem.

Huntington Bank to Acquire Cadence Bank 

Transaction Value: $7.4 Billion

Industry: Banking

Huntington is acquiring Cadence Bank to strengthen its regional banking presence.

The $7.4 billion deal accelerates market penetration across the South and Midwest.

The combined entity gains improved asset quality, scale, and cost efficiencies.

Qualtrics XM Acquires Press Ganey for $6.8 Billion

Transaction Value: $6.8 Billion

Industry: Technology

Qualtrics is purchasing healthcare experience analytics leader Press Ganey for $6.8B.

The deal expands Qualtrics’ footprint in patient, provider, and healthcare experience management. Press Ganey benefits from Qualtrics’ AI-driven insights and global SaaS distribution.

SoftBank Acquires ABB Group Unit for $5.4 Billion

Transaction Value: $5.4 Billion

Industry: Banking

SoftBank is acquiring ABB Group assets in a $5.4B robotics-focused transaction.

The deal deepens SoftBank’s automation and robotics portfolio amid surging AI-driven industrial demand. ABB gains capital to focus on core electrification and automation segments.

FAQs — Intellizence M&A Dataset

What is included in the Intellizence M&A Dataset?

The Intellizence M&A dataset includes verified information on mergers, acquisitions, divestitures, buyouts, and strategic investments. Each record typically includes deal value, acquirer, target, date, transaction type, sector, and source links.

How does Intellizence source M&A data?

Intellizence aggregates and verifies deal information from trusted public sources, including press releases, regulatory filings, investor announcements, and global news wires. The data is curated with human oversight to ensure accuracy and timeliness.

Who uses Intellizence’s M&A data?

Sales and marketing teams, GTM platforms, AI agents, investment analysts, private equity firms, banks, consultants, and risk-intelligence teams rely on Intellizence for deal sourcing, competitive intelligence, opportunity identification, and market monitoring.

Can I integrate M&A data into my product or workflows?

Yes. Intellizence offers API access, daily alerts, and deep integrations to help power sales intelligence tools, AI models, CRM workflows, dashboards, and investment research platforms.

 Want to keep track of the largest Mergers & Acquisitions (M&A) deals in 2024? Check out The Intellizence Mergers & Acquisitions (M&A) Deals. 

Check out last week’s five biggest M&A deals.

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